Healthy Effectual Anti Estrogen Steroids 4-Androstenedione 4-AD CAS 63-05-8 USP Standard

Healthy Effectual Anti Estrogen Steroids 4-Androstenedione 4-AD CAS 63-05-8 USP Standard

1 . Basic view of 4-Androstenedione

Synonyms: 4-Androstenedione(4AD); 3,17-Dioxoandrost-4-Ene;delta-(sup4)-Androsten-3,17-dione;delta(Sup4)-Androstene-3,17-dione;delta4-androsten-3,17-dione;delta-4-androstenedione;SKF 2170;skf2170;4-AD

CAS: 63-05-8

MF: C19H26O2

MW: 286.41

EINECS: 200-554-5

Purity: 98.88%

Manufacturer: Kafen

Characters: Near white crystalline powder, soluble in ethanol, insoluble in water

2 . Usage

Testo-ster-one precursor and metabolite with androgenic activity. Controlled substance (anabolic steroid); Simplified hormone drugs, from the testis or urine extracted with the role of a male hormone steroids, norethisterone, testosterone propionate in the middle body, is widely used in small rheumatoid arthritis, diuretic, and a variety of contraceptive to control infectious inflammation.

3 . Detailed Description

4-Androstenedione can be synthesized in one of two ways. The primary pathway involves conversion of 17-hydroxypregnenolone to dehydroepiandrosterone by way of 17,20-lyase, with subsequent conversion of dehydroepiandrosterone to 4-Androstenedione via the enzyme 3-β-hydroxysteroid dehydrogenase. The secondary pathway involves conversion of 17-hydroxyprogesterone, most often a precursor to cortisol, to 4-androstenedione directly by way of 17,20-lyase. Thus, 17,20-lyase is required for the synthesis of 4-androstenedione, whether immediately or one step removed.  

The production of adrenal 4-Androstenedione is governed by ACTH, whereas production of gonadal 4-Androstenedione is under control by gonadotropins. In premenopausal women, the adrenal glands and ovaries each produce about half of the total 4-androstenedione(about 3 mg/day). After menopause, 4-androstenedione production is about halved, due primarily to the reduction of the steroid secreted by the ovary. Nevertheless, 4-androstenedione is the principal steroid produced by the postmenopausal

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