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Antimony has few biological or medical applications. Antimony containing medicine is a kind of emetic. Antimony compounds are also used as insect antigens. Since 1919, antimony potassium tartrate (commonly known as tartar emesis) has been used as a drug to treat schistosomiasis. It was gradually replaced by praziquantel. Antimony and its compounds are used in a variety of veterinary medicines, such as Amphymalin (lithium antimony thiomalate) as a skin conditioner for ruminants. Antimony can nourish and regulate keratinized tissues, at least for animals.

Antimony mainly exists in the sulfide mineral stibnite (Sb2S3) in nature. Antimony compounds are known to have been used as cosmetics in ancient times. Antimony metal is also recorded in ancient times, but it was mistaken for lead at that time. Around the 17th century, it was known that antimony was a chemical element.