Monosulfiram

Sr.

TEST

RESULT

SPECIFICATION

1

Characteristics

Yellowish brown liquid

A yellow or yellowish Brown solid. Odour sulphurous. Practically insoluble in water. Freely soluble in organic Solvents. Practically insoluble in acids and in alkalis

2

Identification

a) Absorption 1.32

Light Absorption in the Range 230 to 350 nm of 0.002% w/v In Methanol exhibits a well defined Maximum only at 281nm. The absorption at 281nm  is about 1.3

b) complies

Dissolve 0.1 gm in mixture of 0.15 ml of a1% w/v Solution of copper II sulphate And 5Ml of ethanol (96%), Evaporate on water bath and Dissolve the residue in Chloroform. A deep yellowish Brown colour is produced.

C) complies

Boil 0.1 g with 2M hydrochloric acid. Fumes are Evolved which turn lead Acetate paper black

3

Freezing point

30.0°C

28.5°C to 32.0°C

4

Related substances

Complies

Shall comply to the requirements of BP 1993

5

Sulphated Ash

0.072%w/w

Not more than 0.1%w/w

6

Water

0.78%w/w

Not more than 1.0%w/w

7

Assay (On anhydrous Basis)

99.10%

98.0% to 101.0%